Archive for the ‘Biotechnology & Biomedicine’ Category

Grand Challenges: Gates Foundation Grant Supports Tissue Engineered Model of Lymphatic System

May 21, 2013 — Georgia Tech has won a Grand Challenges Explorations award to develop a tissue-engineered model of the human lymphatic system that will support laboratory research into lymphatic filariasis, a parasitic disease known to cause elephantiasis. According to the World Health Organization, the mosquito-borne disease affects more than 120 million persons in tropical areas of the world, and can cause severe disfigurement.

Learning from Ants: Principles of Locomotion in Confined Spaces Could Help Future Robot Teams Work Underground

May 20, 2013 — Future teams of subterranean search and rescue robots may owe their success to the lowly fire ant, a much despised insect whose painful bites and extensive networks of underground tunnels are all-too-familiar to people living in the southern United States.

Drug Targeting: Protein Study Suggests Drug Side Effects are Inevitable – and that Basic Physics Enabled Early Biochemistry

May 20, 2013 — A new study of both computer-created and natural proteins suggests that the number of unique pockets – sites where small molecule pharmaceutical compounds can bind to proteins – is surprisingly small, meaning drug side effects may be impossible to avoid. The study also found that the fundamental biochemical processes needed for life could have been enabled by the simple physics of protein folding.

Oxygen-Free: RNA Was Capable of Catalyzing Electron Transfer on Early Earth with Iron’s Help, Study Suggests

May 19, 2013 — A new study shows how complex biochemical transformations may have been possible under conditions that existed when life began on the early Earth. The study shows that RNA is capable of catalyzing electron transfer under conditions similar to those of the early Earth.

Brain Development: Study Shows How Pathway Competition Affects Early Differentiation of Higher Brain Structures

April 27, 2013 — A new study shows how the strength and timing of competing molecular signals during brain development has generated natural and presumably adaptive differences in a brain region known as the telencephalon — much earlier than scientists had previously believed.

Shape Changers: Surface Diffusion Plays a Significant Role in Defining the Shapes of Catalytic Nanoparticles

April 9, 2013 — Controlling the shapes of nanometer-sized catalytic and electrocatalytic particles made from noble metals such as platinum and palladium may be more complicated than previously thought. Using systematic experiments, researchers have investigated how surface diffusion – a process in which atoms move from one site to another on nanoscale surfaces – affects the final shape of the particles.

Sticky Signature: Adhesive Force Differences Enable Separation of Stem Cells to Advance Potential Therapies and Accelerate Research

April 7, 2013 — A new separation process that depends on an easily-distinguished physical difference in adhesive forces among cells could help expand production of stem cells generated through cell reprogramming. By facilitating new research, the separation process could also lead to improvements in the reprogramming technique itself and help scientists model certain disease processes.

Regulating Cells: Mechanical Forces Play a Major Role in Assembly and Disassembly of a Protein Essential to Many Cell Functions

March 20, 2013 — Researchers have for the first time demonstrated that mechanical forces can control the depolymerization of actin, a critical protein that provides the major force-bearing structure in the cytoskeletons of cells. The research suggests that forces applied both externally and internally may play a much larger role than previously believed in regulating a range of processes inside cells.

Cochlear Implants: Research is Expected to Improve Hearing for Implant Recipients

March 19, 2013 — A team of researchers at Georgia Tech has developed a new type of interface between cochlear implant devices and the brain that could dramatically improve the sound quality of the next generation of implants. Cochlear implants help deaf individuals perceive sound.

Startup Launched from Georgia Tech-Emory University Research Receives $7.9 Million in Venture Capital, Pharma Investment

March 18, 2013 — Clearside Biomedical, Inc. an Atlanta-based ophthalmic pharmaceutical company launched from research at Emory University and the Georgia Institute of Technology, has received $7.9 million in funding to continue drug and technology development for treatment of ocular diseases.